Postdoctoral studies, employing Bioinformatic gene-expression analysis in Neurobiology (scholarship)

Karolinska Institutet

  • Stockholm
  • Permanent
  • Heltid
  • 12 dagar sedan
Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Clinical GeriatricAre you an enthusiastic and ambitious researcher with an interest in neurobiology and bioinformatics? We are searching for a postdoctoral fellow to conduct groundbreaking gene expression analyses in neurodegenerative diseases. Take the opportunity to work in an international environment with world-leading research and contribute to the development of new diagnostic biomarkers and treatment strategies for Alzheimer's disease.Do you want to contribute to top quality medical research?DivisionThe division of Clinical Geriatrics consists of a multi-disciplinary team of 100 employees and affiliates, at the forefront of translational Alzheimer's disease (AD) research using cutting-edge technology with aims to develop new diagnostic biomarkers and new treatment strategies in AD. We work in an inter-disciplinary environment which provides ample opportunities to enhance our understanding and skills.DutiesOur group specializes in therapeutic applications targeting cholinergic pathways, primarily using Nerve Growth Factor (NGF) via encapsulated cell (EC Biodelivery) or cholinesterase inhibitors (ChEI's) towards Alzheimer's disease (AD) therapy. We aim to further our work by performing in-depth gene expression analysis from high-throughput sequencing projects, employing in-vitro, preclinical and clinical studies.This position involves designing and executing experiments, data management and analysis, manuscript preparation, presenting research, contributing to grant proposals and mentoring students. The candidate will analyze and integrate next-generation sequencing data and have the opportunity to publish in high-profile papers, with national and international collaborations.The ideal candidates should hold a PhD in Bioinformatics, Computational Biology or a related field, with experience in omics data analysis (e.g., single-cell RNA-seq, bulk RNA-seq, ChIP-seq, methylation data, or any other). Proficiency in analyzing single-cell ATAC-seq and spatial transcriptomics, programming languages and advanced bioinformatic tools is an asset. The candidate should have an interest in neurodegenerative diseases and a proven record of high-quality scientific research and publications. Excellent verbal and written English skills and the ability to write and apply for grants are required.We are looking for a self-motivated scientist who can coordinate collaborative projects.Entry requirementsPostdoctoral scholarships may be established for foreign researchers who pursue their merit in Sweden. A foreign researcher is a person living in another country who comes to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education at KI. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four-year period following the receipt of a doctoral degree or equivalent.To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate, or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post-doctoral education.What do we offer?A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site.Location: Flemingsberg, StockholmType of scholarshipThe amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.Application processAn application must contain the following documents in English or Swedish:
  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
The application is to be submitted on the Varbi recruitment system.Want to make a difference? Join us and contribute to better health for allThe Department of Neurobiology, Care Sciences and Society (NVS) conducts world leading research in aging, dementia, epidemiology and care sciences. This research extends from basic molecular and cell levels to clinical research and societal studies. NVS educates almost a third of KI students at basic and advanced levels. The Department has approximately 540 employees and a revenue 2023 of 530 million SEK. It comprises seven divisions, located at Campus Flemingsberg and Campus Solna.The Division of Clinical Geriatric, with over 100 employed and affiliated researchers are located both in Neo, Campus Flemingsberg and in the Q-building in Solna. We conduct research focusing on cognitive impairment, dementia, and other aging related disorders, and education, among other medical graduates. Our research is multi-faceted and is in close collaboration with leading institutions and clinics worldwide. The research is clinically oriented with an emphasis on diagnosis, prevention and treatment. The division has a close cooperation with the Medical Unit Aging within Theme Inflammation and Aging at Karolinska University Hospital.

Karolinska Institutet