Postdoctoral studies in in defining Epithelial Tumor Cell Niches (scholarship)

Karolinska Institutet

  • Stockholm
  • Permanent
  • Heltid
  • 1 dag sedan
Do you want to contribute to top quality medical research?A postdoctoral scholarship is available in the lab of Genander at the Department of Cell and Molecular Biology, Karolinska Institutet. More information about the Genander lab can be found here:DivisionThe Genander lab is interested in understanding development and maintenance of epithelial tissues and how alterations in progenitor cells and their environment contribute to disease. The advertised project aims to characterize the functional relevance of progenitor-to-tumor cell niche transitions, focusing on the esophageal epithelium.DutiesThe current project will be centered around characterizing changes in local cell-cell networks during early esophageal epithelial transformation. We have recently described how the esophageal epithelium is regionalized, and how local cell-cell networks and transcriptional signatures contribute to epithelial homeostasis. We are now interested in understanding how these local cell architectures change during tumor initiation. This work will include characterization of epithelial, stromal and immune cell populations in esophageal tissue using a variety of mouse models, organoid co-cultures and spatial sequencing technologies to identify relevant cell-cell interactions.We seek a curious, highly motivated, and creative postdoc with a strong background in cell or tissue biology. The ideal candidate should have practical experience working with mouse models and analyzing sequencing data. Experience with organoid cultures and molecular biology is a strength. Excellent interpersonal and communication skills (in English written and verbal) is required. Emphasis will be also placed on personal suitability, fitting well into the current research group.Entry requirementsPostdoctoral scholarships may be established for foreign researchers who pursue their merit in Sweden. A foreign researcher is a person living in another country who comes to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education at KI. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four-year period following the receipt of a doctoral degree or equivalent.To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate, or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post-doctoral education.What do we offer?A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site.Location: StockholmType of scholarshipThe amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.Application processAn application must contain the following documents in English or Swedish:
  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
  • Relevant references
The application is to be submitted on the Varbi recruitment system.Want to make a difference? Join us and contribute to better health for all

Karolinska Institutet