Postdoctoral Researcher in Circadian organ communication and proteomics

Solna, Stockholm
Tillfälligt
Heltid

13 dagar sedan

Do you want to contribute to top quality medical research?As a postdoc in this project, you will be part of KIRI, the Karolinska Institutet Research Incubator, a unique initiative at KI to build a community for interdisciplinary research and breakthrough discoveries. You will have access to two PI:s that you can meet and interact with to facilitate the research process and increase the synergetic effects. You will also have the opportunity to meet other KIRI postdocs, present your work at scientific events, and take part in KIRI activities. Read more about KIRI here:Your missionCircadian rhythms are controlled by internal clocks present in all organs, with the liver playing a central role in coordinating rhythms across the body through secreted signals. Preliminary findings suggest that the liver influences gene expression in other tissues, such as fat, via time-dependent secretion of specific proteins. This project will combine expertise in chronobiology and cutting-edge proteomics to identify and characterize these liver-derived signals. The overall goal is to understand how the circadian system coordinates communication between organs to maintain physiological balance.

Perform LC/MS based proteomic analyses of circulating proteins and assess their impact on organs in mouse models and cell cultures.
Analyze and interpret omics data using bioinformatic pipelines in Python and R.
Perform experiments in cell culture and animal models to validate the findings.
Coordinate the collaboration between the chronobiology lab (led by Dr. Paul Petrus) and the proteomics lab (led by Dr. Amir Saei).

Your profileTo be eligible for employment as a postdoctor, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier.In addition to the above requirements for the position:

PhD in molecular biology, biochemistry, or a related field
Experience working with mouse models (perform injection, organ/blood collection etc.)
Proficiency in Python or R for bioinformatic analysis
Strong scientific communication skills in English, both oral and written

Meritorious for the position:

Experience from work with cell culture systems
Previous research in circadian biology or endocrinology
Hands-on experience with plasma or tissue proteomics
Experience with collaborative projects in academia and/or industry

What do we offer?A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.Location: SolnaApplicationAn employment application must contain the following documents in English or Swedish:

PhD certificate
A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
A complete list of publications
A summary of current work (no more than one page)

Welcome to apply at the latest September 11.The application is to be submitted through the Varbi recruitment system.Want to make a difference? Join us and contribute to better health for all! Anställningsform: särskild visstidsanställning | Anställningens omfattning: heltid | Antal lediga befattningar: 1 | Sysselsättningsgrad: 100 % | Ort: Solna | Län: Stockholms län | Land: Sweden | Referensnummer: STÖD 2-3243/2025 | Kontakt: Paul Petrus paul.petrus@ki.se, Paul Petrus paul.petrus@ki.se, | Facklig företrädare: Helin Norberg, SACO helin.norberg@ki.se, Helin Norberg, SACO helin.norberg@ki.se, Bodil Moberg , ST-OFR bodil.moberg@ki.se, Bodil Moberg , ST-OFR bodil.moberg@ki.se, Elisabeth Valenzuela, SEKO elizabeth.valenzuela@ki.se, Elisabeth Valenzuela, SEKO elizabeth.valenzuela@ki.se, | Publicerat: 2025-08-19 | Sista ansökningsdag: 2025-09-11

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